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ELISA MAX Deluxe Set Human CCL20 (MIP-3 Alpha) 5 Plates

Réf. UGAP : 3689309 Réf. Fournisseur : 441404 Réf. Constructeur : 441404
ELISA MAX Deluxe Set Human CCL20 (MIP-3 Alpha) 5 Plates
ELISA MAX Deluxe Set Human CCL20 (MIP-3 Alpha) 5 Plates
Franco de port et d'emballage pour toutes les commandes supérieures à 80€ HT.

Produit ni repris ni échangé excepté en cas d’erreur du prestataire.
La quantité choisie doit être comprise entre 1 et 999 999.
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Points clés

Please contact our sales representative for bulk pricing quotations. CCL20 (MIP-3α) belongs to the CC chemokine family. Human CCL20 is a protein of 96 amino acids, which shares 28% amino acid identity with MIP-1β and 64% amino acid sequence identity with mouse CCL20. CCL20 is produced by activated monocytes, T cells, neutrophils, endothelial cells, epithelial cells and fibroblasts. Its expression is induced by lipopolysaccharide (LPS) and inflammatory cytokines such as tumor necrosis factor, IL-1β and interferon-γ, and downregulated by IL-10. CCL20 is the ligand for chemokine receptor CCR6, which is expressed on memory T cells, B cells, and immature dendritic cells (DCs). Therefore, it is involved in the regulation of DC trafficking and recruitment and activation of T cells. CCL20 also has potent antimicrobial activity. Upregulation of CCL20 plays important roles in autoimmune pathogenesis of the central nerve system (MS), pathogenesis of encephalomyelitis, psoriasis, rheumatoid arthritis, and inflammatory bowel diseases. CCL20 is also involved in various cancers, such as gastrointestinal cancers, pancreatic cancer, hepatocellular carcinoma, and breast cancer. The BioLegend ELISA MAX™ Deluxe Set is a sandwich Enzyme-Linked Immunosorbent Assay (ELISA). The human CCL20 (MIP-3α) capture antibody is first coated on a 96-well plate. Standards and samples are added to the wells and CCL20 (MIP-3α) binds to the immobilized capture antibody. Next, biotinylated anti-human CCL20 (MIP-3α) detection antibody is added, producing an antibody-antigen-antibody “sandwich”. Avidin horseradish peroxidase is subsequently added, followed by TMB Substrate Solution, producing a blue color in proportion to the concentration of CCL20 (MIP-3α) present in the sample. Finally, the Stop Solution changes the reaction color from blue to yellow, and the microwell absorbance is read at 450 nm with a microplate reader.;

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Description

Please contact our sales representative for bulk pricing quotations. CCL20 (MIP-3α) belongs to the CC chemokine family. Human CCL20 is a protein of 96 amino acids, which shares 28% amino acid identity with MIP-1β and 64% amino acid sequence identity with mouse CCL20. CCL20 is produced by activated monocytes, T cells, neutrophils, endothelial cells, epithelial cells and fibroblasts. Its expression is induced by lipopolysaccharide (LPS) and inflammatory cytokines such as tumor necrosis factor, IL-1β and interferon-γ, and downregulated by IL-10. CCL20 is the ligand for chemokine receptor CCR6, which is expressed on memory T cells, B cells, and immature dendritic cells (DCs). Therefore, it is involved in the regulation of DC trafficking and recruitment and activation of T cells. CCL20 also has potent antimicrobial activity. Upregulation of CCL20 plays important roles in autoimmune pathogenesis of the central nerve system (MS), pathogenesis of encephalomyelitis, psoriasis, rheumatoid arthritis, and inflammatory bowel diseases. CCL20 is also involved in various cancers, such as gastrointestinal cancers, pancreatic cancer, hepatocellular carcinoma, and breast cancer. The BioLegend ELISA MAX™ Deluxe Set is a sandwich Enzyme-Linked Immunosorbent Assay (ELISA). The human CCL20 (MIP-3α) capture antibody is first coated on a 96-well plate. Standards and samples are added to the wells and CCL20 (MIP-3α) binds to the immobilized capture antibody. Next, biotinylated anti-human CCL20 (MIP-3α) detection antibody is added, producing an antibody-antigen-antibody “sandwich”. Avidin horseradish peroxidase is subsequently added, followed by TMB Substrate Solution, producing a blue color in proportion to the concentration of CCL20 (MIP-3α) present in the sample. Finally, the Stop Solution changes the reaction color from blue to yellow, and the microwell absorbance is read at 450 nm with a microplate reader.;

Documents annexes

Caractéristiques

Fournisseur
BioLegend Europe BV
Marque
BIOLEGEND
Référence fabricant
441404
Référence distributeur
441404
Vendu par
5 plates
Quantité
N/A
Lieu de fabrication
USA
Lieu de stockage
Pays-Bas ou USA
Soumis à carboglace
non
Classement dans le catalogue fournisseur
ELISA Kit
Certification
RUO
Type d’application
ELISA
Type de produit
kit
Température de conservation (°C)
entre 2 et 8 °C
Température de transport
ambiante
Méthode de détection
colorimétrique
Méthode de dosage
ELISA
Organisme cible
Human
Matière dangereuse
non
Code douanier
38220000
Classement NCBI
6364
Nomenclature Nacres
NA.84
Nomenclature CEA
SGP01
Nomenclature IRSN
273
Nomenclature INSERM
NA.NA84
Nomenclature CNRS
NA84
Nomenclature CHU
18.551
Nomenclature DGOS
LD11AOOO
Reprise en cas d’erreur client
non

Fournisseur

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Fournisseur

BIOLEGEND INC

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