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ELISA MAX Deluxe Set Human CXCL10 (IP-10) 5 Plates

Réf. UGAP : 3689179 Réf. Fournisseur : 439904 Réf. Constructeur : 439904
ELISA MAX Deluxe Set Human CXCL10 (IP-10) 5 Plates
ELISA MAX Deluxe Set Human CXCL10 (IP-10) 5 Plates
Franco de port et d'emballage pour toutes les commandes supérieures à 80€ HT.

Produit ni repris ni échangé excepté en cas d’erreur du prestataire.
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Points clés

Please contact our sales representative for bulk pricing quotations. CXCL10, also known as IP-10, is a glutamic acid-leucine-arginine motif negative chemokine structurally and functionally related to MIG (CXCL9) and ITAC (CXCL11). CXCL10 is induced in a variety of cells in response to interferon-γ and lipopolysaccharide. These cell types include monocytes, macrophages, fibroblasts, and epithelial cells. CXCL10 (IP-10) chemoattracts CD4+ and CD8+ T cells, NK, and NKT cells via binding to its receptor CXCR3, which is shared with MIG and ITAC. CXCL10 inhibits neovascularization in tumors and in wound healing in vivo. It also has anti-proliferative effects on endothelial cells in vitro, and angiostatic and antitumor effects in vivo. It has been suggested that the antiproliferative effect of CXCL10 in endothelial cells is CXCR3-independent and that it is mediated through glycosaminoglycan interaction. CXCL10 also possesses antimicrobial activity against E. coli and L. monocytogenes, and both the spore and bacillus forms of B. anthracis. It has been reported that CXCL10 may be important in the pathogenesis of chronic HCV infection, and the circulating CXCL10 concentration was increased in the early and subclinical stage of Type I diabetes patients. CXCL10 was significantly up-regulated in the salivary glands of patients with Sjögren's Syndrome. It also has been reported that CXCL10 was increased in the urine of patients with pulmonary diseases in the absence of renal dysfunction. Both the ELISA MAX™ Set Standard and ELISA MAX™ Set Deluxe are specifically engineered for accurate recovery and measurement of analytes in complex fluids, such as serum and plasma (as well as activated cell cultures) without any interference by confounding serum factors, such as heterophilic antibody or rheumatoid factor.;

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Description

Please contact our sales representative for bulk pricing quotations. CXCL10, also known as IP-10, is a glutamic acid-leucine-arginine motif negative chemokine structurally and functionally related to MIG (CXCL9) and ITAC (CXCL11). CXCL10 is induced in a variety of cells in response to interferon-γ and lipopolysaccharide. These cell types include monocytes, macrophages, fibroblasts, and epithelial cells. CXCL10 (IP-10) chemoattracts CD4+ and CD8+ T cells, NK, and NKT cells via binding to its receptor CXCR3, which is shared with MIG and ITAC. CXCL10 inhibits neovascularization in tumors and in wound healing in vivo. It also has anti-proliferative effects on endothelial cells in vitro, and angiostatic and antitumor effects in vivo. It has been suggested that the antiproliferative effect of CXCL10 in endothelial cells is CXCR3-independent and that it is mediated through glycosaminoglycan interaction. CXCL10 also possesses antimicrobial activity against E. coli and L. monocytogenes, and both the spore and bacillus forms of B. anthracis. It has been reported that CXCL10 may be important in the pathogenesis of chronic HCV infection, and the circulating CXCL10 concentration was increased in the early and subclinical stage of Type I diabetes patients. CXCL10 was significantly up-regulated in the salivary glands of patients with Sjögren's Syndrome. It also has been reported that CXCL10 was increased in the urine of patients with pulmonary diseases in the absence of renal dysfunction. Both the ELISA MAX™ Set Standard and ELISA MAX™ Set Deluxe are specifically engineered for accurate recovery and measurement of analytes in complex fluids, such as serum and plasma (as well as activated cell cultures) without any interference by confounding serum factors, such as heterophilic antibody or rheumatoid factor.;

Documents annexes

Caractéristiques

Fournisseur
BioLegend Europe BV
Marque
BIOLEGEND
Référence fabricant
439904
Référence distributeur
439904
Vendu par
5 plates
Quantité
N/A
Lieu de fabrication
USA
Lieu de stockage
Pays-Bas ou USA
Soumis à carboglace
non
Classement dans le catalogue fournisseur
ELISA Kit
Certification
RUO
Type d’application
enzyme-linked immunosorbent assay
Type de produit
ELISA Kit
Température de conservation (°C)
entre 2 et 8 °C
Température de transport
ambiante
Méthode de détection
colorimétrique
Méthode de dosage
ELISA
Organisme cible
Human
Matière dangereuse
non
Code douanier
38220000
Classement NCBI
3627
Nomenclature Nacres
NA.84
Nomenclature CEA
SGP01
Nomenclature IRSN
273
Nomenclature INSERM
NA.NA84
Nomenclature CNRS
NA84
Nomenclature CHU
18.551
Nomenclature DGOS
LD11AOOO
Reprise en cas d’erreur client
non

Fournisseur

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Fournisseur

BIOLEGEND INC

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