HTRF - Foxo1 phospho-s256 kit - 500 tests 1 Kit

Alternative ELISA et WB, plus simple, plus rapide, très sensible, facilement miniaturisable / automatisable et peu onéreuse.

The phospho-FoxO1 (Ser256) assay is designed for the robust quantification of FoxO1 modulation, phosphorylated on Ser256, as an indicator of its inactivation. FoxO1 is a member of the Forkhead transcription factor FOXO subfamily, and is highly expressed in insulin-responsive tissues where it regulates glucose/lipid metabolism and stress resistance. It also functions as a tumor suppressor by inhibiting cell proliferation. FoxO1 deregulation plays a critical role in the development of metabolic disorders such as diabetes and NAFLD. Its dysfunction is also linked to various types of cancer.