HTRF - Her3 phospho-y1289 kit - 500 tests 1 Kit

Alternative ELISA et WB, plus simple, plus rapide, très sensible, facilement miniaturisable / automatisable et peu onéreuse.

The phospho-HER3 (Tyr1289) assay is designed for the robust quantification of HER3  (Erbb3) modulation when phosphorylated on Tyr1289, an indicator of many types of cancer pathologies. Overexpression of HER3, or human epidermoid receptor 3/ ErbB3, is considered as an indicator for a poor prognosis in human breast cancer. Heterodimerization of HER3 with HER2 is associated with an increase in the aggressiveness of a breast cancer. HER3 is also been found to be involved in prostate, gastric, colon, or other carcinomas. This makes HER3 a key target for anti-cancer therapies.