HTRF - Hif-1 alpha kit - 500 tests 1 Kit

Alternative ELISA et WB, plus simple, plus rapide, très sensible, facilement miniaturisable / automatisable et peu onéreuse.

HIF-1a is one of the 2 subunits of the transcription factor hypoxia-inducible factor-1 (HIF-1). HIF-1 acts as a master regulator of cellular and systemic response to hypoxia by activating the translation of genes involved in energy metabolism, angiogenesis, and apoptosis, among others. High levels of HIF-1 have been associated with aggressive tumor progression. HIF-1a is also strongly linked to diabetes through its involvement in the glucose uptake of target cells. It has also been implicated in diabetes complications, such as diabetic nephropathy or diabetic wound repair.