HTRF - Human il17a/il17ra binding - 500 tests 1 Kit

Alternative ELISA et WB, plus simple, plus rapide, très sensible, facilement miniaturisable / automatisable et peu onéreuse.

Interleukin 17A, a pro-inflammatory cytokine, belongs to a family of six cytokines; IL-17A, IL-17B, IL-17C, IL-17D, IL-E, and IL-17F. IL-17A binds a heterodimeric cell surface receptor (IL-17RA/IL-17RC), triggering a signaling cascade that results in NF-κB activation which leads to the stimulation of the pro-inflammatory cytokines IL-6 and IL-8. Although this cytokine exerts a protective role against many pathogens, the overproduction of IL-17A is associated with autoimmune diseases such as psoriasis, rheumatid arthritis, and Crohn's Disease.