HTRF - Smad3 phospho-s423/425 - 500 tests 1 Kit

Alternative ELISA et WB, plus simple, plus rapide, très sensible, facilement miniaturisable / automatisable et peu onéreuse.

This HTRF cell-based assay enables the rapid, quantitative detection of Phosphorylated SMAD3 phosphorylated at Serine 423/425 as a readout of TGF-ß signaling activity. TGF-ß receptors directly activate SMAD3 by phosphorylation at Ser423/425 causing it to translocate to the nucleus and regulate gene expression involved in apoptosis, migration and differentiation, as well as in immune/inflammatory responses and extracellular matrix remodeling.