HTRF - Stat6 phospho-y641 - 500 tests 1 Kit

Alternative ELISA et WB, plus simple, plus rapide, très sensible, facilement miniaturisable / automatisable et peu onéreuse.

This cell-based assay is designed to monitor the phosphorylation of STAT6 on Tyr641, which represents a hallmark of its activation. STAT6 is a transcription factor mainly activated by the IL4 receptor, and also by the IL3, IL13 or IFNa receptor. STAT6 is phosphorylated on tyrosine 641 by Janus kinases, which leads to the formation of homodimers or heterodimers with STAT2. Finally, activated STAT6 translocates to the nucleus and mediates cytokine-induced gene expression.