HTRF - Tgf beta - 500 tests 1 Kit

Alternative ELISA et WB, plus simple, plus rapide, très sensible, facilement miniaturisable / automatisable et peu onéreuse.

TGF beta 1 (Transforming Growth Factor Beta-1) is considered one of the major cytokines involved in the regulation of extracellular matrix (ECM) synthesis and degradation, as well as a major profibrotic factor. TGF beta 1 pre-proprotein is processed to generate a latency-associated peptide (LAP) and a mature TGFß1 peptide, which remain associated through strong non-covalent interactions. An activation step (MMP2 cleavage or acid activation) is required to release the active form of TGF beta 1 from the TGFß1-LAP complex. Assessment of serum samples often requires enhanced sensitivity. In some cases, AlphaLISA assays may have sufficient sensitivity to enable the detection of low levels of analytes in serum or plasma. Check out the Human TGF-β1 AlphaLISA kitand the TGF-β1 AlphaLisa biotin-free kit’s analytical performances for more information or learn more about AlphaLISA. When assaying, always follow the recommended protocol and avoid highly haemolyzed samples.