Ap3m1 (human) recombinant (full len ght protein gsttag) 25 µg

The protein encoded by this gene is the medium subunités of AP-3, which is an adaptor-related protein complex associated with the Golgi region as well as more peripheral intracellular structures. AP-3 facilitates the budding of vesicles from the Golgi membrane and may be directly involved in protein sorting to the endosomal/lysosomal system. AP-3 is a heterotetrameric protein complex composed of two large subunitéss (delta and beta3), a medium subunités (mu3), and a small subunités (sigma 3). Mutations in one of the large subunitéss of AP-3 have been associated with the Hermansky-Pudlak syndrome, a genetic disorder characterized by defective lysosome-related organelles. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq]