Brca2 (human) recombinant (partial protein gst tag) 25 µg
Produit ni repris ni échangé excepté en cas d’erreur du prestataire.
Points clés
Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele. [provided by RefSeq]
Garantie
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Description
Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele. [provided by RefSeq]
Caractéristiques
- Domaine de recherche
- protéomique
- Fournisseur
- FISHER SCIENTIFIC S.A.S.
- Marque
- ABNOVA
- Référence fabricant
- H00000675-Q01
- Référence distributeur
- 16132341
- Vendu par
- 25 ug
- Quantité
- N/A
- Lieu de fabrication
- Taiwan
- Lieu de stockage
- France
- Délai de péremption à la date de livraison
- 12 mois
- Code à barre
- non
- Soumis à carboglace
- oui
- Libellé produit fabricant
- 25ug brca2 (human) recombinant protein (q01)
- Certification
- RUO
- Marquage CE DIV
- non
- Type de produit
- protéine
- Type de protéine
- oui
- Type d'antibiotique
- non
- Type d'enzyme
- non
- Température de conservation (°C)
- -80 °C
- Température de transport
- carboglace
- Dispositif stérile
- non
- Type d'acide nucléique extrait
- non
- Origine humaine
- non
- Sans composant animal
- non
- Matière dangereuse
- non
- Autres caractéristiques
- Abnova Human BRCA2 Partial ORF (NP_000050, 3319 a.a. - 3418 a.a.) Recombinant Protein with GST-tag at N-terminal, Quantity: 25 ug, Format: Liquid, Formulation: 50mM Tris-HCI, 10mM reduced Glutathione, pH-8.0 in the elution buffer., Host Species: Whea
- Classification REACH
- non
- Code douanier
- 38229000
- Nomenclature Nacres
- NA.55
- Nomenclature CEA
- SGP01
- Nomenclature IRSN
- 273
- Nomenclature INSERM
- NA.NA55
- Nomenclature CNRS
- NA55
- Nomenclature CHU
- 18.551
- Nomenclature DGOS
- LD10AOOO
- Type d'échantillon
- protéine
- Reprise en cas d’erreur client
- non
- Type d’application
- ELISA, Western-Blot
