Cox17 (human) recombinant (full len ght protein gsttag) 25 µg

Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunitéss encoded by mitochondrial genes and multiple structural subunitéss encoded by nuclear genes. The mitochondrially-encoded subunitéss function in electron transfer, and the nuclear-encoded subunitéss may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunités, but may be involved in the recruitment of copper to mitochondria for incorporation into the COX apoenzyme. This protein shares 92% amino acid sequence identity with mouse and rat Cox17 proteins. This gene is no longer considered to be a candidate gene for COX deficiency. A pseudogene COX17P has been found on chromosome 13. [provided by RefSeq]