Gabrb3 (human) recombinant (partial protein gst tag) 10 µg

This gene encodes a member of the ligand-gated ionic channel family. The encoded protein is one of at least 13 distinct subunitéss of a multisubunités chloride channel that serves as the receptor for gamma-aminobutyric acid, the major inhibitory transmitter of the nervous system. This gene is located on the long arm of chromosome 15 in a cluster with two genes encoding related subunitéss of the family. Mutations in this gene may be associated with the pathogenesis of Angelman syndrome, Prader-Willi syndrome, and autism. Alternatively spliced transcript variants encoding isoforms with distinct signal peptides have been described. [provided by RefSeq]