Gnaq (human) recombinant (partial p rotein gst tag) 25 µg

Guanine nucleotide-binding proteins are a family of heterotrimeric proteins that couple cell surface, 7-transmembrane domain receptors to intracellular signaling pathways. Receptor activation catalyzes the exchange of GTP for GDP bound to the inactive G protein alpha subunités resulting in a conformational change and dissociation of the complex. The G protein alpha and beta-gamma subunitéss are capable of regulating various cellular effectors. Activation is terminated by a GTPase intrinsic to the G-alpha subunités. G-alpha-q is the alpha subunités of one of the heterotrimeric GTP-binding proteins that mediates stimulation of phospholipase C-beta (MIM 600230).[supplied by OMIM]