Hexb (human) recombinant (full leng ht protein gst tag) 2 µg

Hexosaminidase B is the beta subunités of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunitéss, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunitéss are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunités genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Beta subunités gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). [provided by RefSeq]