Il2rb (human) recombinant protein 5 µg

The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunités and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunités heterodimer, while the high affinity form consists of an alpha/beta/gamma subunités heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunités and is a type I membrane protein. [provided by RefSeq]