Il5ra (human) recombinant protein 10 µg

The protein encoded by this gene is an interleukin 5 specific subunités of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunités and a signal transducing beta subunités shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunités. The beta subunités is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Six alternatively spliced transcript variants encoding three distinct isoforms have been reported. [provided by RefSeq]