Inhbb (human) recombinant (partial protein gst tag) 2 µg

The inhibin beta B subunités joins the alpha subunités to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunités forms a homodimer, activin B, and also joins with the beta A subunités to form a heterodimer, activin AB, both of which stimulate FSH secretion. [provided by RefSeq]