Lig4 (human) recombinant (partial p rotein gst tag) 25 µg
Produit ni repris ni échangé excepté en cas d’erreur du prestataire.
Points clés
The protein encoded by this gene is a DNA ligase that joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. This protein is essential for V(D)J recombination and DNA double-strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X-ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA-dependent protein kinase (DNA-PK). Both XRCC4 and DNA-PK are known to be required for NHEJ. The crystal structure of the complex formed by this protein and XRCC4 has been resolved. Defects in this gene are the cause of LIG4 syndrome. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq]
Garantie
Garantie 0 Mois
Description
The protein encoded by this gene is a DNA ligase that joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. This protein is essential for V(D)J recombination and DNA double-strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X-ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA-dependent protein kinase (DNA-PK). Both XRCC4 and DNA-PK are known to be required for NHEJ. The crystal structure of the complex formed by this protein and XRCC4 has been resolved. Defects in this gene are the cause of LIG4 syndrome. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq]
Caractéristiques
- Domaine de recherche
- protéomique
- Fournisseur
- FISHER SCIENTIFIC S.A.S.
- Marque
- ABNOVA
- Référence fabricant
- H00003981-Q01
- Référence distributeur
- 16127401
- Vendu par
- 25 ug
- Quantité
- N/A
- Lieu de fabrication
- Taiwan
- Lieu de stockage
- France
- Délai de péremption à la date de livraison
- 12 mois
- Code à barre
- non
- Soumis à carboglace
- oui
- Libellé produit fabricant
- 25ug lig4 (human) recombinant protein (q01)
- Certification
- RUO
- Marquage CE DIV
- non
- Type de produit
- protéine
- Type de protéine
- oui
- Type d'antibiotique
- non
- Type d'enzyme
- non
- Température de conservation (°C)
- -80 °C
- Température de transport
- carboglace
- Dispositif stérile
- non
- Type d'acide nucléique extrait
- non
- Origine humaine
- non
- Sans composant animal
- non
- Matière dangereuse
- non
- Autres caractéristiques
- Abnova Human LIG4 Partial ORF (AAH37491, 802 a.a. - 911 a.a.) Recombinant Protein with GST-tag at N-terminal, Quantity: 25 ug, Format: Liquid, Formulation: 50mM Tris-HCI, 10mM reduced Glutathione, pH-8.0 in the elution buffer., Host Species: Wheat Ge
- Classification REACH
- non
- Code douanier
- 38229000
- Nomenclature Nacres
- NA.55
- Nomenclature CEA
- SGP01
- Nomenclature IRSN
- 273
- Nomenclature INSERM
- NA.NA55
- Nomenclature CNRS
- NA55
- Nomenclature CHU
- 18.551
- Nomenclature DGOS
- LD10AOOO
- Type d'échantillon
- protéine
- Reprise en cas d’erreur client
- non
- Type d’application
- ELISA, Western-Blot
