Myh7 (human) recombinant (partial p rotein gst tag) 25 µg

Muscle myosin is a hexameric protein containing 2 heavy chain subunitéss, 2 alkali light chain subunitéss, and 2 regulatory light chain subunitéss. This gene encodes the beta (or slow) heavy chain subunités of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunités of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy. [provided by RefSeq]