Ppm1f (human) recombinant (full len ght protein gsttag) 25 µg
Produit ni repris ni échangé excepté en cas d’erreur du prestataire.
Points clés
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined. [provided by RefSeq]
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Description
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined. [provided by RefSeq]
Caractéristiques
- Type de protéine
- oui
- Type d'antibiotique
- non
- Certification
- RUO
- Type d'enzyme
- non
- Marquage CE DIV
- non
- Code à barre
- non
- Domaine de recherche
- protéomique
- Marque
- ABNOVA
- Référence distributeur
- 16103972
- Soumis à carboglace
- oui
- Température de conservation (°C)
- -80 °C
- Fournisseur
- FISHER SCIENTIFIC S.A.S.
- Délai de péremption à la date de livraison
- 12 mois
- Dispositif stérile
- non
- Température de transport
- carboglace
- Type d'acide nucléique extrait
- non
- Origine humaine
- non
- Sans composant animal
- non
- Vendu par
- 25 ug
- Classification REACH
- non
- Nomenclature IFPEN
- NA.55
- Nomenclature Nacres
- NA.55
- Nomenclature CEA
- SGP01
- Nomenclature IRSN
- 273
- Nomenclature INSERM
- NA.NA55
- Nomenclature CNRS
- NA55
- Nomenclature CHU
- 18.551
- Nomenclature DGOS
- LD10AOOO
- Code douanier
- 38229000
- Type de produit
- protéine
- Reprise en cas d’erreur client
- non
- Libellé produit fabricant
- 25ug ppm1f (human) recombinant protein (p01)
- Type d’application
- ELISA, western blot
- Lieu de stockage
- France
- Lieu de fabrication
- Taïwan
- Autres caractéristiques
- Abnova Human PPM1F Full-length ORF (NP_055449.1, 1 a.a. - 454 a.a.) Recombinant Protein with GST-tag at N-terminal, Quantity: 25 ug, Format: Liquid, Formulation: 50mM Tris-HCI, 10mM reduced Glutathione, pH-8.0 in the elution buffer., Host Species: Wh
- Type d'échantillon
- protéine
- Matière dangereuse
- non
- Quantité
- N/A
- Référence fabricant
- H00009647-P01
