Prkacb (human) recombinant protein 5 µg

cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunitéss. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunitéss bound to four cAMP and two free monomeric catalytic subunitéss. Four different regulatory subunitéss and three catalytic subunitéss have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunités of cAMP-dependent protein kinase. Three alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq]